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Neupril Pure Methylfolate

Neupril Pure Methylfolate

 (4.8 Based on 2512 Reviews)
Regular price $49.99
Regular price $49.99 Sale price $69.99
SAVE 28% Sold out

5-MTHF + B12 Complex

  • Supports methylation & brain health
  • Clears brain fog & reduces fatigue
  • Boosts focus, clarity, & sustained energy
  • Promotes balanced stress response
  • Nourishes healthy skin & stronger hair
  • Active folate and B12
  • 30-day guarantee

BUNDLE & SAVE

Neupril L-Methylfolate + Methyl-B12 supplement bottle and packaging with berries on a light blue background

Neupril Pure Methylfolate

Regular price $49.99
Regular price $49.99 Sale price $69.99
SAVE 28% Sold out

Why Neupril?

It's Simple!

Neupril Pure Methylfolate gives you the active form of folate your body can readily use. This is especially important if you have an MTHFR gene variant.

Comprehensive: L-Methylfolate is the bioactive form of folate, supporting mood, focus, energy, and overall neurological health, without the conversion issues linked to MTHFR.

Delicious: A smooth berry liquid that makes daily nutrition an easy habit you'll want to keep.

Portable: Designed to fit your lifestyle, whether at work, home, or on the go. Just measure and take.

No Mess, No Stress: Forget the pills and chalky powders. One liquid solution for simple, effective nutrition.

Ingredients & Allergies

Ingredients

Neupril features a precise blend of ultra-high-potency, bioactive nutrients including 15 mg of L-Methylfolate (as L-5-Methylfolate, calcium salt) and 1000 mcg of Vitamin B12 (as Methylcobalamin) per serving. These active forms are specifically chosen for their superior bioavailability, ensuring you receive the most effective nutritional support for neurological health, cognitive function, and cellular energy.

Our liquid formula is crafted with clean, simple, and organic ingredients. The base consists of Reverse Osmosis Water and Organic Vegetable Glycerin, which acts as a natural, plant-based stabilizer. To ensure a pleasant experience, we use an Organic Berry Flavor system derived from Organic Acacia Gum and natural flavors, balanced with Citric Acid for freshness.

Neupril is 100% vegan, gluten-free, soy-free, dairy-free, and non-GMO. We take pride in a "clean label" approach: No artificial ingredients, no preservatives, and no synthetic dyes or sweeteners.

Lastly, Neupril is a liquid-drop formulation designed for maximum absorption. By avoiding the pectin or gelatin bases found in gummies, we deliver pure nutrients directly either under the tongue or easily added to water, juice, or your favorite smoothie.

Allergies

Neupril is entirely plant-based and vegan. These drops are free from gluten, dairy, soy, and nuts. Formulated without synthetic sweeteners, artificial additives, or synthetic dyes, it is a pure choice for sensitive systems.

Science & Certifications

Clinically Tested

Neupril is built on science and formulated with ingredients supported by decades of clinical research. This advanced adult supplement with methylfolate is designed for real absorption and impact, helping you get exactly what you need to function clearly and feel balanced. With a high-potency dose of 15 mg L-Methylfolate and 1000 mcg of Methyl B12, it is not just about convenience. It's about effectiveness you can truly feel.

Third-Party Testing

Every batch of Neupril undergoes rigorous third-party testing to ensure safety, potency, and label accuracy. We test for heavy metals, microbial contaminants, and ingredient integrity so you can feel confident about what you are putting in your body. Neupril is synonymous with methylated B12 and methylfolate, which is clean, effective, and transparent. Our "clean label" approach ensures that every 0.5 ml serving is free from artificial ingredients and preservatives.

Certifications

Neupril is manufactured in NSF, GMP-certified, and FDA-registered facilities in the United States. We prioritize high standards at every step, from sourcing our bioactive L-5-Methylfolate and Methylcobalamin to final bottling, to ensure consistent quality you can trust.

Directions

Each bottle of Neupril provides ultra-high potency methylfolate and bioactive B12. Give the bottle a quick shake and take 10 droplets or .5ml once daily. These can be taken under the tongue or easily added to water, juice, or your favorite smoothie for a daily boost to cognitive clarity and energy.

Benefits

The benefits of Neupril Pure Methylfolate could fill a whole list. Try saying all of this in one breath: improved mood, sharper focus, relief from fatigue, MTHFR support, balanced neurotransmitter function, homocysteine regulation, cardiovascular health, emotional well-being, nerve function support, healthy skin and hair, cognitive longevity, better sleep, steady energy, stress resilience, and overall brain and body wellness.

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VEGAN

NO ARTIFICIAL INGREDIENTS

BIOAVAILABLE FORM

THIRD-PARTY TESTED (FOR HEAVY METALS & MIRCOBES)

NON-GMO

VEGAN

NO ARTIFICIAL INGREDIENTS

BIOAVAILABLE FORM

THIRD-PARTY TESTED (FOR HEAVY METALS & MIRCOBES)

NON-GMO

VEGAN

NO ARTIFICIAL INGREDIENTS

BIOAVAILABLE FORM

THIRD-PARTY TESTED (FOR HEAVY METALS & MIRCOBES)

NON-GMO

VEGAN

NO ARTIFICIAL INGREDIENTS

BIOAVAILABLE FORM

THIRD-PARTY TESTED (FOR HEAVY METALS & MIRCOBES)

NON-GMO

Neupril has helped hundreds of thousands of customers focus—and follow through.

Don't just take our word for it. See for yourself what Neupril customers experience within 60 days of taking methylfolate + methyl B12.

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    Week 1

    Lift the fog, feel the difference

    Methylfolate supports neurotransmitter synthesis, helping clear brain fog and calm anxious thoughts.*

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    Month 1

    Real natural energy, not caffeine highs

    Steady methylation support helps boost dopamine and serotonin for more focus, drive, and a balanced mood. Without the crash.*

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    Month 3

    Break the burnout cycle

    Consistent use supports nervous system recovery and resilience, helping you stay clear-headed, motivated, and grounded even under stress or during recovery.*

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    Month 6

    Rebuild focus and emotional balance

    Long-term use strengthens attention, mood stability, and motivation. Helping you feel more like yourself again.*

    Neupril Methylfolate liquid supplement drops in an amber bottle with a precision glass dropper.

    Clinically Backed Nutrients For Real, Noticeable Benefits

    • Pure L-Methylfolate raw ingredient powder for Neupril high-bioavailability supplements

      L-5-methyltetrahydrofolate (L-5-MTHF)

      KEY FUNCTION
      Supports methylation and neurotransmitter production

    • Highly bioavailable Methylcobalamin Vitamin B12 liquid concentrate for Neupril professional-grade supplements.

      Methylcobalamin (Methyl-B12)

      KEY FUNCTION
      Supports energy production and neurological function

      Benefits You Can See and Feel

      Icon representing sustained natural energy and vitality
      Clean Energy

      Gives your cells the raw material to convert food into sustained energy without the crash.

      deep Sleep

      Supports restful sleep by promoting healthy serotonin and melatonin production naturally.

      Icon representing mood balance and emotional support.
      Mood Boost

      Helps your body produce serotonin and dopamine naturally to support emotional balance and well-being.

      Neupril L-Methylfolate and Methyl-B12 vitamin liquid dietary supplement bottles in a floating group shot

      DNA & Detox

      Activates your body's master regulator for gene expression, cellular repair, and toxin clearance.

      Icon representing enhanced mental clarity and focus
      Sharp Focus

      Sharpens mental clarity and concentration by supporting the neurotransmitters your brain relies on.

      Icon representing overall brain health and neurological function
      Brain Health

      Fuels the neurotransmitters your mind runs on for sharper thinking and lasting mental clarity.

      Us vs. Them

      Not overhyped or overpriced. Just pure methylfolate + methyl B12 made enjoyable and for every unique brain.

      Macro close-up of a glass dropper tip filled with red liquid L-Methylfolate supplement showing bubbles and detail against a light blue background

      Tested, Trusted, and Certified

      Neupril’s methylfolate is third-party tested to confirm purity, potency, and safety, ensuring every drop meets clinical standards and is free from heavy metals, microbes, and unwanted fillers.

      Gluten Free

      USA Made

      Clinical Studies

      Quality Verified

      • ★★★★★

        THE BEST form of the folicacid you can get and I lovethis brand! Worth its moneyand actually helped me a
        lot!

        Chris G.

      • ★★★★★

        Love this brand and the effectiveness of this Methylfolate! It helps my energy, hormones, and even sleep quality. It absorbs better and faster than other
        brands I've had, and it tastes good!

        Kylie L.

      • ★★★★★

        Love these supplements! Have been taking these pre pregnancy and now that I'm pregnant. I have the MTFHR gene mutation and love that these are methylated.

        Lauren B.

          FAQs

          How quickly will I notice results?

          Most customers report improved focus, energy, and mood within the first few days of consistent use, with more noticeable benefits appearing after 2-4 weeks.

          Are these safe for daily use?

          Yes, Neupril Pure Methylfolate are crafted with natural, high-quality ingredients that are safe for everyday use without harsh side effects. Consult your healthcare provider if you have any specific medical concerns.

          Can I take methylfolate with other supplements or medications?

          Generally, yes. But it’s best to talk to your healthcare provider if you're other medications or supplements.

          Does body weight affect how many drops I should take?

          Not necessarily. Dosage isn’t determined by weight. it’s determined by your body’s methylation needs. Everyone processes folate differently depending on factors like genetics (such as MTHFR variants), stress levels, diet, and overall methylation efficiency. A heavier person doesn’t automatically need more drops. The recommended 10-drop dose is designed to support optimal methylation for most adults. If needed, adjustments should be made based on how you feel or under the guidance of a healthcare professional.

          What if I don't know if I have MTHFR?

          Even without the MTHFR mutation, methylfolate is still the superior form of folate. Instead of relying on conversion steps, Neupril provides the body with the active form of folate it can use immediately enhancing focus, improving mood, and boosting natural energy.

          What does Neupril taste like?

          At Neupril, our drops have a refreshing organic berry flavor that’s light, smooth, and easy to take. Whether under the tongue or mixed into a drink, most people find it pleasantly subtle. Not too sweet, not too strong. Just clean, natural berry goodness you’ll actually enjoy taking every day.